Cht is a mixed mode resin.
Hydroxyapatite ceramic type.
Details of the binding mechanism are described in chapter 3.
This is an easy to use mixed mode medium which is both ligand and support matrix in one.
It s a spherical ceramic form of crystalline hydroxyapatite and this form allows it to be used in production scale columns at high flow rates while maintaining its unique separation properties.
Both types have elution characteristics similar to crystalline hydroxyapatite but also have some important differences.
In an ask the expert webinar on 18 july.
Ceramic hydroxyapatite cht for commercial purification ceramic hydroxyapatite is one of the leading media for biomolecule purification.
Two types of chemically pure ceramic hydroxyapatite cht ceramic hydroxyapatite types i and ii are produced.
Two types of cht ceramic hydroxyapatite type i and type ii are available in three particle sizes 20 40 and 80 µm.
Two types of cht ceramic hydroxyapatite type i and type ii are available in three particle sizes 20 40 and 80 μm.
Bio rad s cht ceramic hydroxyapatite xt cht xt calcium affinity cation exchange chromatography medium is used for purifying numerous types of biomolecules with single step clearance of impurities and aggregates in monoclonal antibody mab purification.
The duration and temperature of the sintering step determine whether the ceramic hydroxyapatite is cht type i or type ii.
Cht type i has a higher protein binding capacity and better capacity for acidic proteins.